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Melanotan-1 (afamelanotide) daily dose in human research typically ranges from 0.25mg to 1mg subcutaneously, administered once daily over 24 weeks

This suggests a partial recovery after exercise

Here are a few root causes to look into that may trigger symptoms of POTS: Mineral deficiency Nervous system dysfunction Lyme disease Post-COVID Mitochondria dysfunction Parasites Surgery Mold toxicity Heavy metal toxicity Low nitric oxide Viral infections Trauma Chronic inflammation The Relationship Between POTS and COVID There are some infections that put you at a higher risk for developing POTS, including the recent coronavirus infection